Antigenic properties of cultured tumor cell lines derived from spleens of Friend virus-infected BALB/c and BALB/c-H-2b mice.

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Antigenic properties of cultured tumor cell lines derived from spleens of Friend virus-infected BALB/c and BALB/c-H-2b mice

BALB/c-H-2b (BALB.B) mice are less susceptible to the Friend virus (FV) disease syndrome than congenic BALB/c (H-2d) mice, and spleen cells from FV-infected BALB.B mice are markedly less tumorigenic on transplantation to syngeneic hosts than those from FV-infected BALB/c mice. For these reasons we investigated the expression of FV-associated cell surface antigens on cultured, FV-trnasformed cel...

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Properties of cell lines derived from tumors induced by Friend virus in BALB/c and BALB/c-H-2b mice

Cell lines have been established in culture from Friend virus-induced tumors of BALB/c (H-2d) and congenic BALB/c-H-2b (BALB.B) origin. Spleens from virus-infected hosts in the terminal stages of erythroleukemic disease provided tissues for the establishment of subcutaneously transplantable tumors of both strains. Subsequently cells of these tumors were introduced into culture and passed serial...

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PROPERTIES OF CELL LINES DERIVED FROM TUMORS INDUCED BY FRIEND VIRUS IN BALB/c AND BALB/c-H-2b MICE* BY HERBERT A. FREEDMAN$ AND FRANK LILLY

Genes located at the Fu-1, Fu-2, and H-2 chromosomal regions are the major polymorphic systems in the mouse which govern the pathological consequences of inoculation with Friend virus (FV) (reference 1 and footnote 1) . Fu-1 and Fu-2 appear to govern susceptibility to the helper virus component and to the defective SFFV1 component, respectively, of the FV complex, both of which are necessary fo...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1975

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.142.6.1365